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Not every cat has significant side effects to ketamine, otherwise the drug would be pulled off the market. The problem that has been encountered with Savannahs is that when they do have a poor response, it is much worse then the typical reaction. With most cats the reaction is over with in a matter of minutes so the owner is never aware of it. With some Savannahs, the paranoid hallucinations have been known to go on for hours.
